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Using two separate drugs to shed weight can be very effective you can find combinations before the FDA now awaiting approval. When dealing with fat loss and the individuals who go through it one should err along the side of caution and let the FDA do its job and demand some investigation be done in order that the public is aware of the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies are in business to make money and that they would say anything to keep people on their medications. Researchers found out that participants using this drug for any year, lost excess weight within a month and have kept the body weight off through the 56 weeks from the study. Contrave is often a combination of the drugs naltrexone and bupropion, which appears to reflect a brand new trend of weight-loss drugs which might be made up of more than one active ingredient, that might make them more effective and safer. Combo-pilling could be the newest fad or better yet the newest ahead under scrutiny and so it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that by using a combination of pills is becoming popular is the fact that since right now there are not any long term prescription weightloss pills that have been approved by the FDA aside from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications and some of the combinations happen to be rejected or have yet to be authorized by the FDA. Seizures can be a side effect with Contrave and really should not be taken in individuals with seizure disorders. The drug also can raise blood pressure and heart rate, and really should not be used in individuals with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise hypertension and heartrate and must not be used in patients with uncontrolled high blood pressure levels, along with by you are not heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients using a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients to the increased risk of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stopping smoking. 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